Get Me There. San Francisco to Des Moines
1,545 mi · 1 stop The cheapest round trip from San Francisco to Des Moines right now is $266 — Dec 20 → 24, 4 nights, 1 stop.
Best fare
Des Moines Dec 20 → 24 · 4 nights · 1 stop
Above typical for this route ($226–$245) — it usually dips lower.
Prices checked on Oct 12
By month
October 2026 $352
November 2026 $277
December 2026cheapest $266
January 2027 $318
February 2027 $307
March 2027 $369
April 2027 $458
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Price history
13 weeks tracked · weekly lows
All dates (713 priced)
Dec 20 → 24 4 nights · 1 stop
Dec 16 → 20 4 nights · 1 stop
Dec 17 → 20 3 nights · 1 stop
Nov 21 → 26 5 nights · 1 stop
Nov 2 → 6 4 nights · 1 stop
Nov 6 → 9 3 nights · 1 stop
Nov 13 → 16 3 nights · 1 stop
Dec 5 → 10 5 nights · 1 stop
Dec 12 → 17 5 nights · 1 stop
Dec 2 → 6 4 nights · 1 stop
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