Get Me There. San Francisco to Des Moines
1,545 mi · 1 stop The cheapest round trip from San Francisco to Des Moines right now is $271 — Dec 19 → 24, 5 nights, 1 stop.
Best fare
Des Moines Dec 19 → 24 · 5 nights · 1 stop
Above typical for this route ($232–$253) — it usually dips lower.
Prices checked on Oct 20
By month
October 2026 $420
November 2026 $276
December 2026cheapest $271
January 2027 $281
February 2027 $295
March 2027 $313
April 2027 $478
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Price history
15 weeks tracked · weekly lows
All dates (713 priced)
Dec 19 → 24 5 nights · 1 stop
Nov 13 → 16 3 nights · 1 stop
Jan 12 → 14 2 nights · 1 stop
Nov 11 → 16 5 nights · 1 stop
Nov 12 → 16 4 nights · 1 stop
Nov 14 → 16 2 nights · 1 stop
Dec 10 → 12 2 nights · 1 stop
Dec 10 → 13 3 nights · 1 stop
Dec 10 → 14 4 nights · 1 stop
Dec 10 → 15 5 nights · 1 stop
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