Get Me There. San Francisco to Des Moines
The cheapest round trip from San Francisco to Des Moines right now is $238 — Sep 23 → 28, 5 nights, 1 stop.
Best fare
Des Moines Sep 23 → 28 · 5 nights · 1 stop
In the typical range for this route ($221–$244).
Prices checked on Sep 2
By month
September 2026cheapest $238
October 2026 $238
November 2026 $254
December 2026 $288
January 2027 $337
February 2027 $337
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Price history
8 weeks tracked · weekly lows
All dates (720 priced)
Sep 23 → 28 5 nights · 1 stop
Sep 26 → 28 2 nights · 1 stop
Sep 30 → Oct 5 5 nights · 1 stop
Oct 3 → 5 2 nights · 1 stop
Oct 22 → 26 4 nights · 1 stop
Sep 23 → 25 2 nights · 1 stop
Sep 25 → 28 3 nights · 1 stop
Sep 26 → Oct 1 5 nights · 1 stop
Sep 30 → Oct 2 2 nights · 1 stop
Oct 2 → 5 3 nights · 1 stop
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